The constellation, Orion, rises in the east and sets in the west. Orion’s belt, the only three bright stars (as marked in the image) that form a short straight line in the whole night sky rise very close to due east and set very close to due west.

If you want to be really accurate then the first star in the belt to rise and set, called Mintaka (Among three stars in the Orion Belt it is towards the Betelguese), will always rise and set within one degree of true east and west wherever you are in the world.